Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
3 results
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Malignancy- In which of the following clinical scenarios should cytoreductive surgery and intraperitoneal chemotherapy be considered?
- A 57-year-old woman presents with worsening abdominal fullness and poorly localized abdominal pain. One year ago she had uneventful appendectomy. She brings you her medical showing that a low-grade appendiceal neoplasm was found on pathology. Computed tomography (CT) demonstrates evidence of multiple fluid filled lesions throughout the abdomen. What is the most appropriate next step in her treatment?
- A 62-year-old woman is found to have a large near-obstructing sigmoid cancer on colonoscopy; biopsy returns as adenocarcinoma. Preoperative staging includes a carcinoembryonic antigen (CEA) level of 8 ng/mL, and imaging shows a few prominent lymph nodes near the sigmoid lesion. She is referred for surgical management. Frozen section on peritoneal nodules found near the lesion return as adenocarcinoma, and oncological resection is completed. Which of the following is the best determinant of the prognosis for this patient?