Infectious Colitis
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Perioperative
Benign Disease- A 56-year-old woman with a history of recurrent urinary tract infections presents to the emergency department with tachycardia (heart rate 124 beats/min), hypotension (blood pressure 85/38 mm Hg), diffuse abdominal pain, and frequent watery diarrhea following a course of oral antibiotics. Her abdomen is distended and diffusely tender. Her white blood cell count is 25,000/L (25109/L) and her hemoglobin is 15.0 g/dL (150 g/L). The patient is positive for Clostridioides difficile and is not responding to treatment with 125 mg of oral vancomycin. What is the next best option for this patient?
- A 35-year-old woman presents to the emergency department with a history of profuse watery diarrhea, crampy abdominal pain, and vomiting several days after eating oysters. Her laboratory findings are normal except for a mildly elevated white blood cell count, sodium 129 mEq/L (129 mmol/L), chloride 85 mEq/L (85 mmol/L), and potassium 3.2 mEq/L. Stool cultures are positive. Which pathogen is likely associated with this presentation?
- A 76-year-old woman presents with a history of CHF to the hospital with abdominal pain of 24 hours’ duration and bloody diarrhea. Her temperature is 98.6°F (37.0°C), heart rate 90 beats/min, white blood cell count 16,000/mL (16´109/L), and blood pressure 110/70 mm Hg. Computed tomography imaging is ordered (Figure); Her abdomen is tender but without peritoneal signs. Colonoscopy shows patchy, superficial areas of ulceration and sloughing in the transverse colon. The best next treatment for this patient is which of the following?
- A 23-year-old man with a history of ulcerative colitis is admitted to the hospital with bloody diarrhea. His white blood cell count is 13,000/L (13109/L) and hemoglobin is 8.3 g/dL (83 g/L). He is hemodynamically stable. After hospital admission and initiation of intravenous (IV) steroids and infliximab, he undergoes flexible sigmoidoscopy with biopsy. He continues to have 10 to 12 bloody bowel movements daily. Endoscopic and pathologic findings are shown (Figures 1 and 2). What is the best next step in management?
Anorectal Disease






