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A 28-year-old woman with a 12-year history of Crohn’s disease presents with cramping abdominal pain, a 15-lb (6.8-kg) unintentional weight loss, and recurrent emesis. She has been taking infliximab maintenance therapy for the last 4 years. Magnetic resonance enterography demonstrates multiple short strictures over a 15-cm portion of the mid-jejunum with decompressed distal small bowel. Colonoscopy shows no active perianal or colonic disease. What is the best definitive treatment?

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