Radiation, Microscopic, and Ischemic Colitis
- Radiation injury to the colon and rectum can cause significant morbidity, and effects can be seen many years after initial exposure.
- Surgery should be considered the last resort for radiation injury as complications are frequent. Surgical treatment should be individualized and based on symptoms and clinical context.
- Microscopic colitis is a rare cause of non-bloody diarrhea characterized by nonspecific inflammation in the lamina propria with infiltrates of lymphocytes and plasma cells.
- Budesonide is the only evidence-based treatment of microscopic colitis.
- Ischemic colitis results from disruption of blood flow from small vessels and is distinct from mesenteric ischemia. The treatment of ischemic colitis is based on symptom management and patient optimization.
- Long-term complications of ischemic colitis include strictures and chronic ischemia which may be indications for elective surgery in an otherwise medically optimized patient.
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Last updated: January 26, 2022
Cannon, Jamie A, and Gregory D Kennedy. "Radiation, Microscopic, and Ischemic Colitis." ASCRS Textbook of Colon and Rectal Surgery, 2022. ASCRS U, www.ascrsu.com/ascrs/view/ASCRS-Textbook-of-Colon-and-Rectal-Surgery/2285049/all/Radiation__Microscopic__and_Ischemic_Colitis.
Cannon JA, Kennedy GD. Radiation, Microscopic, and Ischemic Colitis. ASCRS Textbook of Colon and Rectal Surgery. 2022. https://www.ascrsu.com/ascrs/view/ASCRS-Textbook-of-Colon-and-Rectal-Surgery/2285049/all/Radiation__Microscopic__and_Ischemic_Colitis. Accessed December 9, 2023.
Cannon, J. A., & Kennedy, G. D. (2022). Radiation, Microscopic, and Ischemic Colitis. In ASCRS Textbook of Colon and Rectal Surgery https://www.ascrsu.com/ascrs/view/ASCRS-Textbook-of-Colon-and-Rectal-Surgery/2285049/all/Radiation__Microscopic__and_Ischemic_Colitis
Cannon JA, Kennedy GD. Radiation, Microscopic, and Ischemic Colitis [Internet]. In: ASCRS Textbook of Colon and Rectal Surgery. ; 2022. [cited 2023 December 09]. Available from: https://www.ascrsu.com/ascrs/view/ASCRS-Textbook-of-Colon-and-Rectal-Surgery/2285049/all/Radiation__Microscopic__and_Ischemic_Colitis.
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TY - ELEC T1 - Radiation, Microscopic, and Ischemic Colitis ID - 2285049 A1 - Cannon,Jamie, AU - Kennedy,Gregory, Y1 - 2022/01/26/ BT - ASCRS Textbook of Colon and Rectal Surgery UR - https://www.ascrsu.com/ascrs/view/ASCRS-Textbook-of-Colon-and-Rectal-Surgery/2285049/all/Radiation__Microscopic__and_Ischemic_Colitis DB - ASCRS U DP - Unbound Medicine ER -