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A 37-year-old woman with a history of ulcerative colitis underwent restorative proctocolectomy with the construction of a J-pouch ileoanal anastomosis 2 years ago. The patient presents to your clinic with tenesmus of 3 months’ duration, pelvic discomfort, and fecal urgency. Pouchoscopy reveals inflamed pouch mucosa, with normal prepouch ileum. Which medical therapy is the treatment of choice?

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