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A 53-year-old woman presents with a 3×2–cm pruritic, well-circumscribed, eczematous, tender lesion that does not involve the anal verge. A punch biopsy notes intradermal infiltration of cells with large, round, eccentric nuclei, with pale vacuolated cytoplasm, which stain positive for cytokeratin 7. Workup is negative for malignancy. What is the best step in management?
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Citation
"" ASCRS Question Bank, ASCRS U, www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/. Accessed 25 June 2026.
ASCRS Question Bank. https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/. Accessed June 25, 2026.
In ASCRS Question Bank https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/
[Internet]. In: ASCRS Question Bank. [cited 2026 June 25]. Available from: https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/.
* Article titles in AMA citation format should be in sentence-case
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ID - 3717235
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ASCRS Question Bank

