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A 53-year-old woman presents with a 3×2–cm pruritic, well-circumscribed, eczematous, tender lesion that does not involve the anal verge. A punch biopsy notes intradermal infiltration of cells with large, round, eccentric nuclei, with pale vacuolated cytoplasm, which stain positive for cytokeratin 7. Workup is negative for malignancy. What is the best step in management?
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Citation
"" ASCRS Question Bank, ASCRS U, www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/Anorectal_Disease. Accessed 22 April 2026.
ASCRS Question Bank. https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/Anorectal_Disease. Accessed April 22, 2026.
In ASCRS Question Bank https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/Anorectal_Disease
[Internet]. In: ASCRS Question Bank. [cited 2026 April 22]. Available from: https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/Anorectal_Disease.
* Article titles in AMA citation format should be in sentence-case
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T1 -
ID - 3717235
BT - ASCRS Question Bank
UR - https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717235/all/Anorectal_Disease
DB - ASCRS U
DP - Unbound Medicine
ER -
ASCRS Question Bank

