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A 54-year-old woman was referred to you with a newly diagnosed anal squamous cell carcinoma. Physical examination reveals a 1.2-cm distal anal canal lesion and no palpable inguinal lymphadenopathy. Magnetic resonance imaging of the pelvis shows no sphincter involvement and no regional lymphadenopathy. What is the most appropriate next step?
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Citation
"" ASCRS Question Bank, ASCRS U, www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717269/all/. Accessed 23 April 2026.
ASCRS Question Bank. https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717269/all/. Accessed April 23, 2026.
In ASCRS Question Bank https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717269/all/
[Internet]. In: ASCRS Question Bank. [cited 2026 April 23]. Available from: https://www.ascrsu.com/ascrs/view/ASCRS-Question-Bank/3717269/all/.
* Article titles in AMA citation format should be in sentence-case
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ASCRS Question Bank

